ceesdekker.net Secrets

Making use of single-molecule optical and AFM imaging and drive-spectroscopy approaches, we find to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our exploration passions consist of:

You frequently get involved in conversations about science and faith. You may have also composed several textbooks on the subject. Don’t you are convinced sooner or later We're going to know every little thing Which God’s part will be around?

Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I

Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.

2010, developed a different way (‘wedging transfer’) to govern nanostructures; 1st report of DNA translocation as a result of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into strong-condition nanopores

Our analysis ranges in the biophysics of DNA to synthetic cells and over and above. Make sure you take a look down below at the spectrum of our existing projects.

‘Initially we looked at Organic units having a Bodily watch and acted on the basis on the applications we realized. It took a couple of years ahead of we started off working a lot more on the large Organic challenges. I then began to contact it nanobiology, a phrase that did not exist at enough time.

Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim of the pore is highlighted in purple, and a 3D rendering on the motion on the DNA rod is exhibited.

What if, in lieu of employing conventional top rated-down silicon electronics, transistors could possibly be crafted from the bottom up using solitary natural and organic molecules since the switching elements? This idea, which turned The idea of now’s area of molecular electronics, to start with emerged inside the nineteen seventies.

Resolving the move dimension in condensin-pushed DNA loop extrusion identifies ATP binding given that the action-generating procedure

‘The concept that There exists this kind of thing like a starting, a major bang, is already an interesting signpost to take into account that there was a creator. But extra generally, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: essentially, there are actually only atoms and all-natural forces that we are able to measure.

2001, discovery of solitary-electron transistors at area temperature based upon nanotubes; realization of to start with logic circuits with carbon nanotube equipment; and discovery of the molecular structure of DNA fix enzymes with AFM

Developments in nanotechnology while in the nineties designed making Digital products from one molecules a risk. Cees Dekker recounts how his workforce established a home-temperature transistor based on a single carbon nanotube.

Supercoiling-dependent DNA binding: quantitative modeling and applications to cees dekker bulk and one-molecule experiments